Soft Lithographic Procedure for Producing Plastic Microfluidic Devices with View-ports Transparent to Visible and Infrared Light

A soft lithographic approach to fabricate patterned microfluidic channels.

The control of surface properties and spatial presentation of functional molecules within a microfluidic channel is important for the development of diagnostic assays and microreactors and for performing fundamental studies of cell biology and fluid mechanics. Here, we present a simple technique, applicable to many soft lithographic methods, to fabricate robust microchannels with precise contro...

Light Actuated Microfluidic Devices

A light-actuated microfluidic device has been successfully fabricated to inject, move, separate, and merge liquid droplets with nano-liter volumes. Light actuation is realized by sandwiching the liquid droplets between two photosensitive surfaces whose wettability can he changed by light. By integrating a photoconductor with an electrowetting electrode, the surface tension at the liquidsolid in...

Soft Lithographic Fabrication of Micro Optic and Guided Wave Devices

Polymer Embossing Tools for Rapid Prototyping of Plastic Microfluidic Devices

In this work, a new MEMS technology for hot embossing using polydimethylsiloxane (PDMS) tools is developed and characterized. The developed technology will permit low cost, simple, and rapid fabrication of disposable microfluidic biochips and plastic microstructures for numerous BioMEMS applications. For traditional planar systems, a negative photoepoxy (SU-8) or thick positive photoresist (AZ4...

Polymer embossing tools for rapid prototyping of plastic microfluidic devices

In this paper, we describe a simple and rapid method of fabricating hot embossing tools using polydimethylsiloxane (PDMS), which are then used to rapidly fabricate microchannels in polymethylmethacrylate (PMMA). A negative photoepoxy SU-8 or thick positive photoresist AZ4620 on silicon was used for molding during PDMS casting. Fabrication time of these PDMS tools was considerably less than thos...